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Microsoft AI Takes Giant Leap Toward Medical Superintelligence

July 1, 2025

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Microsoft AI has unveiled groundbreaking research that could reshape medical diagnostics. Through the Sequential Diagnosis Benchmark (SDBench), the company tested AI against 304 notoriously complex medical cases from the New England Journal of Medicine. The model-agnostic diagnostic tool, MAI Diagnostic Orchestrator (MAI-DxO), demonstrated 85.5% accuracy, surpassing the average performance of human physicians. By expediting decision-making and reducing costly tests, this innovation offers both precision and cost-effectiveness. Microsoft believes this may be a step toward “medical superintelligence,” described as a system capable of outperforming the collective expertise of global clinicians. While limitations remain, the research signals major implications for health care’s future.

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